exRNAdisease

Entry Detail

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General Information

Database ID: exR0759301 RNA Name: HLA-DQA1 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 32628179 End Site(bp): 32647062 External Links: ENSG00000196735

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF1 chr6 30571393 30597179 + ABI2 chr2 203328239 203447728 + AC006538.2 chr19 2717769 2740048 - AC007192.1 chr19 18153158 18178117 + AC007998.2 chr18 35443871 35497940 - AC011448.1 chr19 19516227 19536076 + AC011462.1 chr19 41350853 41425001 + AC026464.4 chr16 69299682 69322700 + AC068580.4 chr11 1734821 1763954 - AC073082.1 chr2 48632291 48755724 - ACAD11 chr3 132558138 132660082 - ACAD8 chr11 134253495 134265855 + ACTA2 chr10 88935074 88991339 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + ADPRHL2 chr1 36088892 36093932 + AHCY chr20 34280268 34311802 - AHRR chr5 271670 438291 + AIFM1 chrX 130129362 130165887 - AL021997.3 chr6 28267121 28281580 + AL136454.1 chr1 192716132 192716653 + ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005083.1 chr7 20217577 20221700 + AC005899.4 chr17 32328441 32329395 + AC007996.1 chr18 26542971 26545791 - AC010618.3 chr19 17488990 17511889 - AC012236.1 chr15 31221999 31230838 - AC019205.1 chr6 73263212 73301789 + AC099329.1 chr3 42785087 42852428 - AC107027.3 chr3 131455126 131458598 - AD000090.1 chr19 35557956 35581954 + AL031428.1 chr1 23020147 23088058 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.