exRNAdisease

Entry Detail

---



General Information

Database ID: exR0759308 RNA Name: HLA-E RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 30489509 End Site(bp): 30494194 External Links: ENSG00000204592

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AASS chr7 122073549 122144255 - ABCA3 chr16 2275881 2340746 - ABCB6 chr2 219209772 219218994 - ABLIM1 chr10 114431113 114768061 - AC007192.1 chr19 18153158 18178117 + AC011448.1 chr19 19516227 19536076 + AC097637.1 chr3 52221081 52231190 - AC120057.2 chr17 7240427 7244635 - ACTA2 chr10 88935074 88991339 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR8 chr3 53867066 53882152 - ADCY3 chr2 24819169 24919839 - ADPRHL2 chr1 36088892 36093932 + AGFG2 chr7 100539203 100568220 + AHCY chr20 34280268 34311802 - AL133352.1 chr10 100505628 100529881 - AL136454.1 chr1 192716132 192716653 + AL358113.1 chr9 69035747 69255187 + AL928654.3 chr14 105487199 105492267 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3615 chr17 74748663 74748683 + hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC019205.1 chr6 73263212 73301789 + AC026461.1 chr16 56682470 56687807 + AC107926.1 chr17 20963722 20980238 + AF274573.1 chrX 150915813 150920938 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.