exRNAdisease

Entry Detail

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General Information

Database ID: exR0759322 RNA Name: HMGA1 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 34236873 End Site(bp): 34246231 External Links: ENSG00000137309

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTR2 chr2 65227753 65271253 + ADNP chr20 50888916 50931437 - AKR7A2 chr1 19303965 19312146 - ADH5 chr4 99070978 99088801 - ADM chr11 10305073 10307397 + AC008982.1 chr19 38817471 38840178 - ADGRL1 chr19 14147743 14206187 - AGPAT1 chr6 32168212 32178096 - ADGRA3 chr4 22345071 22516066 - AGFG2 chr7 100539203 100568220 + ACLY chr17 41866917 41930542 - AJUBA chr14 22971177 22982551 - AK4 chr1 65147549 65232145 + AAMP chr2 218264123 218270257 - AC009133.6 chr16 29812261 29820092 + AHCYL2 chr7 129225023 129430211 + AC068547.1 chr2 151802651 151973949 - AC015813.2 chr17 57989038 58007246 - AKAP13 chr15 85380571 85749358 + AFTPH chr2 64524305 64593005 + AK5 chr1 77282019 77559966 + ADRM1 chr20 62302093 62308862 + ACER3 chr11 76860867 77026797 + AL121594.1 chr14 35122549 35317474 + ACTA1 chr1 229431245 229434098 - AHCY chr20 34280268 34311802 - ABRACL chr6 139028745 139043302 + ADARB1 chr21 45073853 45226560 + AL136454.1 chr1 192716132 192716653 + ACAD10 chr12 111686056 111757107 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7a-5p chr9 94175962 94175983 + hsa-let-7d-5p chr9 94178841 94178862 + hsa-let-7e-5p chr19 51692793 51692814 + hsa-miR-21-5p chr17 59841273 59841294 + hsa-miR-138-5p chr16 56858527 56858549 + hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-6835-3p chr6 34240714 34240736 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC010331.1 chr19 47607873 47608454 - AC016876.2 chr17 7581964 7584086 - AC019205.1 chr6 73263212 73301789 + AC020663.1 chr16 4730115 4752565 - AC020928.2 chr19 36773712 36775908 - AC025271.4 chr15 57553955 57555680 + AC079781.5 chr7 97851688 97972985 - AC104971.1 chr18 58670009 58671877 - AC126365.1 chr17 20788071 20789584 + AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL117378.1 chr6 131901963 131920565 + AL132780.1 chr14 22929607 22956374 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.