exRNAdisease

Entry Detail

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General Information

Database ID: exR0759344 RNA Name: HNRNPA0 RNA Type: mRNA Chromosome: chr5 Starnd: - Coordinate: Start Site(bp): 137745651 End Site(bp): 137754363 External Links: ENSG00000177733

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AACS chr12 125065434 125143333 + ABCA2 chr9 137007234 137028922 - AC005258.1 chr19 2269525 2341172 + AC006030.1 chr2 74211604 74363377 - AC010422.3 chr19 12643831 12648397 - AC010463.1 chr19 17267418 17282966 + AC087289.3 chr17 75898645 75930129 - AC093525.2 chr16 2496032 2520218 + AC097637.1 chr3 52221081 52231190 - AC099811.2 chr17 42119674 42154916 - AC107871.1 chr15 68184032 68229718 - AC129492.3 chr17 8150816 8162975 - AC135050.2 chr16 31083439 31094956 - ACAT2 chr6 159762045 159779112 + ACOT7 chr1 6264269 6394391 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTN1 chr14 68874143 68979440 - ADAR chr1 154582057 154628013 - AGGF1 chr5 77029251 77065234 + AKAP8 chr19 15353385 15379798 - AKIRIN1 chr1 38991276 39006059 + AL021546.1 chr12 120438198 120460006 + AL117348.2 chr1 225886696 225924278 - AL121594.1 chr14 35122549 35317474 + AL136531.2 chr20 1317571 1393096 - AL365205.1 chr6 41780349 41790141 + ALAS1 chr3 52198086 52214327 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-21-5p chr17 59841273 59841294 + hsa-miR-1181 chr19 10403505 10403525 - hsa-miR-1248 chr3 186786675 186786701 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002094.1 chr17 28357647 28381697 + AC007952.4 chr17 19112000 19112636 - AC010327.5 chr19 55216660 55221616 + AC012485.1 chr2 238231684 238255633 + AC016876.2 chr17 7581964 7584086 - AC068134.2 chr2 232420661 232421461 - AC087190.3 chr16 9104848 9113181 + AC132217.1 chr11 2129121 2129964 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.