exRNAdisease

Entry Detail

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General Information

Database ID: exR0759363 RNA Name: HNRNPUL1 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 41262496 End Site(bp): 41307787 External Links: ENSG00000105323

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC4 chr13 95019835 95301475 - ABCF1 chr6 30571393 30597179 + ABHD2 chr15 89087459 89202355 + AC008763.3 chr19 7678501 7682854 + AC024592.3 chr19 5866171 5903787 - AC026954.2 chr17 7312661 7319174 - AC138811.2 chr16 18788063 18801519 - ACAT2 chr6 159762045 159779112 + ACTB chr7 5527148 5563784 - ADNP2 chr18 80109262 80147523 + AHCY chr20 34280268 34311802 - AIF1L chr9 131096476 131123152 + AKR1A1 chr1 45550543 45570049 + AKT1S1 chr19 49869033 49878459 - AL031708.1 chr16 1632259 1686715 + AL358113.1 chr9 69035747 69255187 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-650 chr22 22822791 22822811 + hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-632 chr17 32350169 32350187 + hsa-miR-1247-5p chr14 101560362 101560383 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026362.1 chr12 122975320 122982907 + AD000090.1 chr19 35557956 35581954 + AL121992.1 chr1 15586136 15603626 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.