exRNAdisease

Entry Detail

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General Information

Database ID: exR0759426 RNA Name: HSPA8 RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 123057489 End Site(bp): 123063230 External Links: ENSG00000109971

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB4 chr7 87401697 87480435 - AC018523.2 chr11 14493783 14520344 - AC004922.1 chr7 99325879 99394653 + ACBD5 chr10 27195214 27242130 - AKIRIN1 chr1 38991276 39006059 + AC008763.3 chr19 7678501 7682854 + AC138811.2 chr16 18788063 18801519 - ADSL chr22 40346500 40390463 + AC008758.1 chr19 12461559 12551474 - ADM chr11 10305073 10307397 + AC009133.6 chr16 29812261 29820092 + AC245033.1 chr15 82536788 82573194 - ACTR1B chr2 97655939 97664044 - AFDN chr6 167826922 167972023 + ABCG2 chr4 88090150 88231628 - AGPAT5 chr8 6708642 6761503 + AKT1 chr14 104769349 104795751 - ACTB chr7 5527148 5563784 - AL133352.1 chr10 100505628 100529881 - ACAA2 chr18 49782164 49813953 - AK4 chr1 65147549 65232145 + AC091959.3 chr5 146203550 146339251 + AGPAT3 chr21 43865223 43987592 + ACTR2 chr2 65227753 65271253 + AC139530.2 chr17 81703371 81720539 + ACAT2 chr6 159762045 159779112 + AL136295.4 chr14 24180395 24190416 - AC091167.2 chr15 90249556 90272208 + AL022238.4 chr22 40346529 40410054 + ACTG1 chr17 81509971 81523847 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-302c-3p chr4 112648366 112648388 - hsa-miR-302a-5p chr4 112648224 112648246 - hsa-miR-632 chr17 32350169 32350187 + hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-4485-3p chr11 10508277 10508296 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008555.5 chr19 34891605 34905139 - AC012236.1 chr15 31221999 31230838 - AC016876.2 chr17 7581964 7584086 - AC040162.3 chr16 67882461 67886367 + AC067852.2 chr17 42552436 42554748 - AC106864.1 chr4 112693047 112706810 - AC132217.1 chr11 2129121 2129964 - AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL023653.1 chrX 129794994 129796963 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.