exRNAdisease

Entry Detail

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General Information

Database ID: exR0759448 RNA Name: HUWE1 RNA Type: mRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 53532096 End Site(bp): 53686728 External Links: ENSG00000086758

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAK1 chr2 69457997 69674349 - AC004922.1 chr7 99325879 99394653 + AC009690.3 chr15 72266746 72319946 - AC010422.3 chr19 12643831 12648397 - AC011455.2 chr19 38915404 38949855 - AC093525.2 chr16 2496032 2520218 + AC120057.2 chr17 7240427 7244635 - ACTG1 chr17 81509971 81523847 - ADAMTS1 chr21 26835755 26845409 - ADCY1 chr7 45574140 45723116 + ADCY6 chr12 48766194 48789037 - ADCY9 chr16 3953387 4116442 - ADGRA2 chr8 37784191 37844896 + AGAP1 chr2 235494043 236131800 + AHNAK chr11 62433542 62556235 - AKAP1 chr17 57085092 57121346 + ALDH5A1 chr6 24494867 24537207 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3654 chr7 133034860 133034878 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC010442.1 chr5 466124 473098 - AC037459.3 chr8 22565997 22567171 - AC091564.7 chr11 6610883 6616594 - AC132217.1 chr11 2129121 2129964 - AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.