Entry Detail


General Information

Database ID:exR0759452
RNA Name:HYOU1
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):119044188End Site(bp):119057227
External Links:ENSG00000149428



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE106804
Description:Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:13
Number of Control:6
Number of Samples:19





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCF2
chr7
151207837
151227166
-
ABI2
chr2
203328239
203447728
+
AC010422.3
chr19
12643831
12648397
-
AC011448.1
chr19
19516227
19536076
+
AC120057.2
chr17
7240427
7244635
-
ACADM
chr1
75724347
75787575
+
ACSL3
chr2
222860942
222944639
+
ADCY3
chr2
24819169
24919839
-
AK2
chr1
33007940
33080996
-
AL121594.1
chr14
35122549
35317474
+
AL136454.1
chr1
192716132
192716653
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-146a-5p
chr5
160485372
160485393
+
hsa-miR-146b-5p
chr10
102436520
102436542
+
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-361-3p
chrX
85903641
85903663
-
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-1286
chr22
20249145
20249165
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009446.1
chr8
71675300
71702786
+
AC079781.5
chr7
97851688
97972985
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:29330365
Title:Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:Nat Commun. 2018 Jan 12;9(1):175.
Description:Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.