exRNAdisease

Entry Detail

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General Information

Database ID: exR0759524 RNA Name: IGF2 RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 2129112 End Site(bp): 2141238 External Links: ENSG00000167244

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AL160269.1 chr9 96235331 96352058 - AC120057.2 chr17 7240427 7244635 - ADAMTSL4 chr1 150549369 150560937 + ADK chr10 74151202 74709963 + ADAR chr1 154582057 154628013 - ADAMTS9 chr3 64515654 64688000 - ACTR1B chr2 97655939 97664044 - ADSL chr22 40346500 40390463 + AL133352.1 chr10 100505628 100529881 - AL121845.3 chr20 63708864 63739103 + ADCY6 chr12 48766194 48789037 - AIF1L chr9 131096476 131123152 + ADRM1 chr20 62302093 62308862 + AKAP1 chr17 57085092 57121346 + AC009133.6 chr16 29812261 29820092 + AL360181.3 chr10 133380017 133420271 + AC068547.1 chr2 151802651 151973949 - ACIN1 chr14 23058564 23095614 - ADAM8 chr10 133262420 133276868 - ALDH16A1 chr19 49453225 49471050 + ACTG1 chr17 81509971 81523847 - AGPAT4 chr6 161129967 161274061 - ADCK2 chr7 140672945 140696261 + ACKR3 chr2 236567787 236582354 + ADAMTS2 chr5 179110853 179345461 - ADGRG6 chr6 142301854 142446266 + AL022238.4 chr22 40346529 40410054 + ADAT1 chr16 75596981 75623300 - ACTR1A chr10 102461881 102502712 - AKIRIN1 chr1 38991276 39006059 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-147a chr9 120244985 120245004 - hsa-miR-218-5p chr5 168768211 168768231 - hsa-miR-147b-3p chr15 45433098 45433118 + hsa-miR-3609 chr7 98881700 98881723 + hsa-miR-4442 chr3 25664875 25664891 - hsa-miR-4485-3p chr11 10508277 10508296 - hsa-miR-6501-5p chr21 33550664 33550685 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002467.1 chr7 107739999 107744581 - AC005562.1 chr17 30576464 30672789 + AC007952.4 chr17 19112000 19112636 - AC010327.5 chr19 55216660 55221616 + AC016876.2 chr17 7581964 7584086 - AC020928.2 chr19 36773712 36775908 - AC022167.2 chr16 8848105 8860456 + AC083964.1 chr8 450714 451343 - AC095057.3 chr4 40166675 40167831 + AC118758.3 chr7 56809214 56848800 - AC132217.1 chr11 2129121 2129964 - AC245014.3 chr1 145281116 145281462 + AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.