exRNAdisease

Entry Detail

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General Information

Database ID: exR0759591 RNA Name: IMP3 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 75639085 End Site(bp): 75648706 External Links: ENSG00000177971

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC10 chr6 43427366 43450427 + AC005258.1 chr19 2269525 2341172 + AC008764.1 chr19 16479067 16628204 - AC118553.2 chr1 99970011 100083321 + AC139530.2 chr17 81703371 81720539 + ACADS chr12 120725774 120740008 + ACAP3 chr1 1292390 1309609 - ACIN1 chr14 23058564 23095614 - ACSL1 chr4 184755595 184826818 - ACTC1 chr15 34790230 34795549 - ACTN4 chr19 38647649 38731589 + AFF1 chr4 86935002 87141054 + AGPAT3 chr21 43865223 43987592 + AGRN chr1 1020120 1056118 + AIMP2 chr7 6009255 6023834 + AKT1 chr14 104769349 104795751 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020928.2 chr19 36773712 36775908 - AC022098.1 chr19 14137146 14171267 + AC084082.1 chr8 66112667 66126632 + AL121992.1 chr1 15586136 15603626 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.