exRNAdisease

Entry Detail

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General Information

Database ID: exR0759645 RNA Name: IPO5 RNA Type: mRNA Chromosome: chr13 Starnd: + Coordinate: Start Site(bp): 97953658 End Site(bp): 98024296 External Links: ENSG00000065150

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAGAB chr15 67200667 67255195 - ABCB7 chrX 75051048 75156732 - ABCC5 chr3 183919934 184017939 - AC008982.1 chr19 38817471 38840178 - AC010132.3 chr7 42909273 42932174 - AC010422.3 chr19 12643831 12648397 - AC015813.2 chr17 57989038 58007246 - AC091167.2 chr15 90249556 90272208 + AC124312.1 chr15 24955034 25000276 + ACAD10 chr12 111686056 111757107 + ACTG1 chr17 81509971 81523847 - ACTR3B chr7 152759749 152855378 + ADCY1 chr7 45574140 45723116 + ADM chr11 10305073 10307397 + ADTRP chr6 11712054 11807046 - AGRN chr1 1020120 1056118 + AGTRAP chr1 11736084 11754802 + AHCY chr20 34280268 34311802 - AKAP10 chr17 19904302 19978343 - AL049629.2 chr11 33698261 33722467 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6850-5p chr8 144791970 144791991 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC132217.1 chr11 2129121 2129964 - AC244153.1 chr17 38450394 38452444 - AL049543.1 chr6 28587378 28591747 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.