exRNAdisease

Entry Detail

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General Information

Database ID: exR0759862 RNA Name: KHSRP RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 6413348 End Site(bp): 6424794 External Links: ENSG00000088247

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AACS chr12 125065434 125143333 + AC010422.3 chr19 12643831 12648397 - AC090360.1 chr18 80034346 80097088 + ACOT7 chr1 6264269 6394391 - ACTB chr7 5527148 5563784 - ADRM1 chr20 62302093 62308862 + AFDN chr6 167826922 167972023 + AGPS chr2 177392757 177559299 + AGRN chr1 1020120 1056118 + AHCY chr20 34280268 34311802 - AJAP1 chr1 4654609 4792534 + AK4 chr1 65147549 65232145 + AKR7A2 chr1 19303965 19312146 - AL121594.1 chr14 35122549 35317474 + ALDH9A1 chr1 165662216 165698863 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-96-5p chr7 129774739 129774761 - hsa-miR-182-5p chr7 129770447 129770470 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC016876.2 chr17 7581964 7584086 - AC105036.3 chr15 75527150 75601205 - AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AL020995.1 chr1 32987075 33032469 + AL121827.2 chr20 63253978 63261615 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.