exRNAdisease

Entry Detail

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General Information

Database ID: exR0759995 RNA Name: KPNB1 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 47649476 End Site(bp): 47685505 External Links: ENSG00000108424

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AARS2 chr6 44298731 44313347 - AC010422.3 chr19 12643831 12648397 - AC011448.1 chr19 19516227 19536076 + AC018523.2 chr11 14493783 14520344 - AC022826.2 chr8 73688691 73878854 - AC046185.1 chr17 63702845 63752097 - AC107871.1 chr15 68184032 68229718 - AC120057.2 chr17 7240427 7244635 - ACACA chr17 37084992 37406836 - ACKR3 chr2 236567787 236582354 + ACTG1 chr17 81509971 81523847 - ADGRA3 chr4 22345071 22516066 - ADH5 chr4 99070978 99088801 - AHCY chr20 34280268 34311802 - AKAP12 chr6 151239967 151358559 + AL136295.1 chr14 24189157 24213473 - AL136295.4 chr14 24180395 24190416 - AL603832.3 chr1 112702614 112711433 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007566.1 chr7 92457564 92495601 + AC020663.1 chr16 4730115 4752565 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.