exRNAdisease

Entry Detail

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General Information

Database ID: exR0760054 RNA Name: LAPTM5 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 30732469 End Site(bp): 30757774 External Links: ENSG00000162511

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD2 chr15 89087459 89202355 + AC004922.1 chr7 99325879 99394653 + AC007192.1 chr19 18153158 18178117 + AC009690.3 chr15 72266746 72319946 - AC010422.3 chr19 12643831 12648397 - AC015813.2 chr17 57989038 58007246 - AC069503.2 chr12 121888809 121921470 + AC104452.1 chr3 49416777 49429314 - AC104472.3 chr3 155763043 155854442 - AC118549.1 chr1 77562416 77683419 - ACAT2 chr6 159762045 159779112 + ACO1 chr9 32384603 32454769 + ACTA1 chr1 229431245 229434098 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - AGPAT1 chr6 32168212 32178096 - AHCY chr20 34280268 34311802 - AKR1A1 chr1 45550543 45570049 + AKT2 chr19 40230317 40285536 - AL121594.1 chr14 35122549 35317474 + AL136454.1 chr1 192716132 192716653 + AL358113.1 chr9 69035747 69255187 + AL645941.2 chr6 32937364 32953122 - ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010226.1 chr5 115602057 115623897 + AC016876.2 chr17 7581964 7584086 - AC040162.3 chr16 67882461 67886367 + AC051619.7 chr15 45200325 45200632 - AC245014.3 chr1 145281116 145281462 + AC245884.11 chr19 54308915 54337168 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.