exRNAdisease

Entry Detail

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General Information

Database ID: exR0760062 RNA Name: LASP1 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 38869859 End Site(bp): 38921770 External Links: ENSG00000002834

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD14A-ACY1 chr3 51974706 51989183 + AC007192.1 chr19 18153158 18178117 + AC010422.3 chr19 12643831 12648397 - AC010463.1 chr19 17267418 17282966 + AC073896.1 chr12 56285916 56316059 - AC093323.1 chr4 6663396 6676755 + ACTG1 chr17 81509971 81523847 - ACTR1B chr2 97655939 97664044 - ACY1 chr3 51983340 51989197 + ADAR chr1 154582057 154628013 - ADM chr11 10305073 10307397 + AGFG2 chr7 100539203 100568220 + AHCYL1 chr1 109984765 110023742 + AIF1L chr9 131096476 131123152 + AKAP17A chrX 1591604 1602520 + AL022238.4 chr22 40346529 40410054 + AL121845.3 chr20 63708864 63739103 + AL132780.3 chr14 22946270 22982258 - AL139011.2 chr1 160216800 160285130 - ALDH18A1 chr10 95605941 95656711 - ALDH5A1 chr6 24494867 24537207 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-28-5p chr3 188688794 188688815 + hsa-miR-147a chr9 120244985 120245004 - hsa-miR-27b-3p chr9 95085505 95085525 + hsa-miR-206 chr6 52144401 52144422 + hsa-miR-342-3p chr14 100109715 100109737 + hsa-miR-193b-3p chr16 14304017 14304038 + hsa-miR-296-3p chr20 58817626 58817647 - hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-873-5p chr9 28888925 28888945 - hsa-miR-1224-5p chr3 184241405 184241423 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC091564.7 chr11 6610883 6616594 - AC132217.1 chr11 2129121 2129964 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.