exRNAdisease

Entry Detail

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General Information

Database ID: exR0760146 RNA Name: LIN28A RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 26410817 End Site(bp): 26429728 External Links: ENSG00000131914

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AHCYL2 chr7 129225023 129430211 + AGAP1 chr2 235494043 236131800 + ACKR3 chr2 236567787 236582354 + AC131160.1 chr3 183815568 183884889 - ACTR3B chr7 152759749 152855378 + AC006064.6 chr12 6556886 6607367 - AC027644.4 chr7 66628958 66811189 + AC008575.1 chr5 112827213 112867582 + AASS chr7 122073549 122144255 - AC073508.2 chr17 40627356 40665141 - ACOT2 chr14 73567620 73575658 + ADAR chr1 154582057 154628013 - AC004832.3 chr22 30409255 30428990 + ABCE1 chr4 145098288 145129524 + AKAP8L chr19 15380050 15419141 - AKR7A2 chr1 19303965 19312146 - ADCY2 chr5 7396138 7830081 + AL139300.1 chr14 103562962 103685924 + ALDH4A1 chr1 18871430 18902724 - AK7 chr14 96392128 96489427 + ABI2 chr2 203328239 203447728 + AC007192.1 chr19 18153158 18178117 + AL138752.2 chr9 37588413 38068687 - AC118549.1 chr1 77562416 77683419 - ACAA1 chr3 38103129 38137242 - ADGRL1 chr19 14147743 14206187 - ADD3 chr10 109996368 110135565 + AK2 chr1 33007940 33080996 - ABHD13 chr13 108218392 108234243 + ACTB chr7 5527148 5563784 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-664b-5p chrX 154768596 154768619 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009446.1 chr8 71675300 71702786 + AC012615.1 chr19 1874871 1876169 - AC016747.4 chr2 61115787 61164825 + AC016876.2 chr17 7581964 7584086 - AC106864.1 chr4 112693047 112706810 - AC114284.1 chr5 120781218 120790778 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL137782.1 chr13 75549773 75807120 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.