exRNAdisease

Entry Detail

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General Information

Database ID: exR0760174 RNA Name: LMNB2 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 2427638 End Site(bp): 2456959 External Links: ENSG00000176619

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AASS chr7 122073549 122144255 - ABI3 chr17 49210411 49223225 + AC005258.1 chr19 2269525 2341172 + AC008878.3 chr19 7382834 7470241 + AC011448.1 chr19 19516227 19536076 + AC138696.1 chr8 143247110 143276403 + AC138811.2 chr16 18788063 18801519 - AC138969.1 chr16 16317444 16350590 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTN4 chr19 38647649 38731589 + ADAM11 chr17 44758988 44781846 + ADD1 chr4 2843857 2930076 + ADK chr10 74151202 74709963 + ADM2 chr22 50481543 50486440 + AGAP1 chr2 235494043 236131800 + AHCY chr20 34280268 34311802 - AHCYL2 chr7 129225023 129430211 + AHSA1 chr14 77457870 77469472 + AKAP17A chrX 1591604 1602520 + AKT1 chr14 104769349 104795751 - AL021546.1 chr12 120438198 120460006 + ALAS1 chr3 52198086 52214327 + ALDH9A1 chr1 165662216 165698863 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4485-3p chr11 10508277 10508296 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL022157.1 chrX 57121662 57127243 + AL096828.3 chr20 63218041 63218502 + AL117335.1 chr20 1888128 1894374 - AL118516.1 chr22 46761894 46762563 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.