exRNAdisease

Entry Detail

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General Information

Database ID: exR0760276 RNA Name: LSM4 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 18306230 End Site(bp): 18323274 External Links: ENSG00000130520

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABR chr17 1003518 1229738 - AC011462.1 chr19 41350853 41425001 + AC026464.4 chr16 69299682 69322700 + AC073508.2 chr17 40627356 40665141 - AC087289.3 chr17 75898645 75930129 - ACADVL chr17 7217125 7225266 + ACTG1 chr17 81509971 81523847 - ACVR2B chr3 38453890 38493142 + ADAR chr1 154582057 154628013 - ADARB1 chr21 45073853 45226560 + AGAP1 chr2 235494043 236131800 + AGFG1 chr2 227472152 227561214 + AGK chr7 141551278 141655244 + AHNAK chr11 62433542 62556235 - AL132671.2 chr6 117318211 117573571 - AL139353.1 chr14 31334312 31457441 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC022167.2 chr16 8848105 8860456 + AC124068.2 chr15 89335053 89336161 + AC139887.2 chr4 760202 781859 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.