exRNAdisease

Entry Detail

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General Information

Database ID: exR0760330 RNA Name: MACF1 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 39081316 End Site(bp): 39487177 External Links: ENSG00000127603

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AADAT chr4 170060222 170091699 - ABCB7 chrX 75051048 75156732 - ABCC1 chr16 15949577 16143074 + ABHD2 chr15 89087459 89202355 + AC124312.1 chr15 24955034 25000276 + ACLY chr17 41866917 41930542 - ADAR chr1 154582057 154628013 - ADCK5 chr8 144373101 144393242 + ADCY6 chr12 48766194 48789037 - ADPGK chr15 72751369 72785846 - ADSL chr22 40346500 40390463 + AL022238.4 chr22 40346529 40410054 + AL139011.2 chr1 160216800 160285130 - AL603832.3 chr1 112702614 112711433 - ALDH18A1 chr10 95605941 95656711 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-624-5p chr14 31014706 31014727 - hsa-miR-5100 chr10 42997630 42997651 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC084082.1 chr8 66112667 66126632 + AD000090.1 chr19 35557956 35581954 + AL049543.1 chr6 28587378 28591747 + AL132780.1 chr14 22929607 22956374 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.