exRNAdisease

Entry Detail

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General Information

Database ID: exR0760426 RNA Name: MARCKSL1 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 32333839 End Site(bp): 32336233 External Links: ENSG00000175130

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCD4 chr14 74285269 74303055 - ABCF3 chr3 184186023 184194012 + AC005832.4 chr12 4604944 4662643 + AC008581.2 chr5 77030902 77152155 + AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC011448.1 chr19 19516227 19536076 + AC012254.2 chr18 47108188 47176345 - AC091959.3 chr5 146203550 146339251 + ACAA1 chr3 38103129 38137242 - ACACA chr17 37084992 37406836 - ACD chr16 67657512 67660815 - ACIN1 chr14 23058564 23095614 - ACO2 chr22 41469117 41528989 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + ADAM17 chr2 9488486 9556732 - ADAMTS13 chr9 133414358 133459402 + ADAMTS2 chr5 179110853 179345461 - ADD1 chr4 2843857 2930076 + ADIPOR1 chr1 202940826 202958572 - AGGF1 chr5 77029251 77065234 + AGL chr1 99850361 99924023 + AHDC1 chr1 27534035 27604431 - AIF1L chr9 131096476 131123152 + AKT1 chr14 104769349 104795751 - AL136454.1 chr1 192716132 192716653 + AL365205.1 chr6 41780349 41790141 + AL807752.6 chr9 137031241 137040436 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7a-5p chr9 94175962 94175983 + hsa-let-7b-5p chr22 46113691 46113712 + hsa-let-7g-5p chr3 52268336 52268357 - hsa-miR-541-3p chr14 101064548 101064569 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026362.1 chr12 122975320 122982907 + AC060780.1 chr17 43148368 43171037 - AC067852.2 chr17 42552436 42554748 - AC069281.2 chr7 100572232 100578700 - AC097359.2 chr3 37241789 37244177 - AC104257.1 chr8 131308545 131317632 + AC112229.4 chr2 110386411 110433673 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.