exRNAdisease

Entry Detail

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General Information

Database ID: exR0760477 RNA Name: MCM7 RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 100092728 End Site(bp): 100101940 External Links: ENSG00000166508

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAR2 chr20 36236459 36270918 + AC010422.5 chr19 12664828 12669397 - AC037459.1 chr8 22589274 22602084 + AC073508.2 chr17 40627356 40665141 - AC091551.1 chr18 50968019 51058144 + AC131160.1 chr3 183815568 183884889 - AC245033.1 chr15 82536788 82573194 - ACADS chr12 120725774 120740008 + ACIN1 chr14 23058564 23095614 - ACTN3 chr11 66546395 66563334 + ACVR1B chr12 51951699 51997078 + ADAMTS1 chr21 26835755 26845409 - ADD2 chr2 70607618 70768225 - ADGRV1 chr5 90529344 91164437 + ADPGK chr15 72751369 72785846 - AGO2 chr8 140520156 140635633 - AHCY chr20 34280268 34311802 - AIF1L chr9 131096476 131123152 + AKT2 chr19 40230317 40285536 - AL513165.2 chr9 37512547 37592469 - ALDH18A1 chr10 95605941 95656711 - ALDH9A1 chr1 165662216 165698863 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-93-5p chr7 100093815 100093837 - hsa-miR-25-5p chr7 100093610 100093630 - hsa-miR-6790-3p chr19 6392925 6392945 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004687.1 chr17 58330884 58332508 - AC016876.2 chr17 7581964 7584086 - AC091493.1 chr3 16687986 16697479 - AC091564.7 chr11 6610883 6616594 - AC106864.1 chr4 112693047 112706810 - AC132217.1 chr11 2129121 2129964 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.