exRNAdisease

Entry Detail

General Information

Database ID:

exR0760494

RNA Name:

MDC1

RNA Type:

mRNA

Chromosome:

chr6

Starnd:

-

Coordinate:

Start Site(bp):

30699807

End Site(bp):

30717447

External Links:

ENSG00000137337

Disease Information

Disease Name:	Glioblastoma Multiforme
Disease Category:	Cancers
MeSH ID:	D005909
Type:	Neoplasms/Neoplasms, Glandular and Epithelial
Alias:	Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID:	GSE106804
Description:	Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:	Cancer vs Control
Case Disease Type:	Glioblastoma Multiforme
Case Disease SubType:	NA
Case Sample:	Glioblastoma Multiforme
Control Sample:	Healthy
Number of Case:	13
Number of Control:	6
Number of Samples:	19

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ABCC1	chr16	15949577	16143074	+
AC000093.1	chr22	19717220	19724772	+
AC107871.1	chr15	68184032	68229718	-
AC118553.2	chr1	99970011	100083321	+
ADAM11	chr17	44758988	44781846	+
ADAM23	chr2	206443532	206621127	+
AEN	chr15	88621337	88632281	+
AFDN	chr6	167826922	167972023	+
AHCY	chr20	34280268	34311802	-
AKAP13	chr15	85380571	85749358	+
AL603832.3	chr1	112702614	112711433	-
AL669918.1	chr6	32813767	32838822	-

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC022150.4	chr19	52650437	52653284	-

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	29330365
Title:	Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:	Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:	Nat Commun. 2018 Jan 12;9(1):175.
Description:	Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.