exRNAdisease

Entry Detail

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General Information

Database ID: exR0760581 RNA Name: MFGE8 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 88898683 End Site(bp): 88913381 External Links: ENSG00000140545

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007040.2 chr2 70939318 70995336 - AC131160.1 chr3 183815568 183884889 - AC245033.1 chr15 82536788 82573194 - ACER3 chr11 76860867 77026797 + ACTN1 chr14 68874143 68979440 - ACVR1B chr12 51951699 51997078 + ADO chr10 62804720 62808479 + ADRA2C chr4 3766348 3768526 + ADSL chr22 40346500 40390463 + AEN chr15 88621337 88632281 + AFG3L2 chr18 12328944 12377227 - AGBL5 chr2 27042364 27070622 + AGO4 chr1 35808016 35857890 + AGRN chr1 1020120 1056118 + AHCY chr20 34280268 34311802 - AL022238.4 chr22 40346529 40410054 + AL359922.1 chr9 21802636 22029594 + AL512785.2 chr1 162365407 162383531 + ALDH3A2 chr17 19648136 19685760 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC144652.1 chr7 155295918 155297541 - AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AF106564.1 chr8 24912165 24914717 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.