exRNAdisease

Entry Detail

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General Information

Database ID: exR0760651 RNA Name: MKNK2 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 2037465 End Site(bp): 2051244 External Links: ENSG00000099875

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCD1 chrX 153724856 153744755 + ABCF2 chr7 151207837 151227166 - ABHD17A chr19 1876810 1885547 - AC010422.3 chr19 12643831 12648397 - AC010531.1 chr16 87302876 87334273 - ACADVL chr17 7217125 7225266 + ACAT2 chr6 159762045 159779112 + ACSL4 chrX 109624244 109733403 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADGRE5 chr19 14380501 14408725 + ADPGK chr15 72751369 72785846 - AHCY chr20 34280268 34311802 - AIP chr11 67483026 67491103 + AK2 chr1 33007940 33080996 - AK4 chr1 65147549 65232145 + AL133352.1 chr10 100505628 100529881 - AL590764.2 chrX 71103987 71111575 - AL928654.3 chr14 105487199 105492267 + ALDH2 chr12 111766887 111817532 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-3654 chr7 133034860 133034878 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008738.7 chr19 33207129 33207639 + AC010997.3 chr10 75279726 75401246 - AC016876.2 chr17 7581964 7584086 - AC245884.11 chr19 54308915 54337168 - AD000090.1 chr19 35557956 35581954 + AL049796.1 chr1 93847174 93848939 + AL138756.1 chr9 112028570 112039143 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.