exRNAdisease

Entry Detail

---



General Information

Database ID: exR0760661 RNA Name: MLLT1 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 6210381 End Site(bp): 6279975 External Links: ENSG00000130382

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD17C chr15 80679684 80755621 + AC007192.1 chr19 18153158 18178117 + AC010422.3 chr19 12643831 12648397 - AC092073.1 chr19 34396315 34409364 + ACIN1 chr14 23058564 23095614 - ACTN4 chr19 38647649 38731589 + ADCY3 chr2 24819169 24919839 - AGRN chr1 1020120 1056118 + AKT2 chr19 40230317 40285536 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-124-3p chr8 64379210 64379231 + hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-149-5p chr2 240456015 240456037 + hsa-miR-302a-3p chr4 112648186 112648208 - hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-373-3p chr19 53788748 53788770 + hsa-miR-449a chr5 55170586 55170607 - hsa-miR-512-3p chr19 53666729 53666750 + hsa-miR-520e-3p chr19 53675764 53675784 + hsa-miR-520d-3p chr19 53720149 53720170 + hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-654-5p chr14 101040234 101040255 + hsa-miR-454-3p chr17 59137787 59137809 - hsa-miR-483-5p chr11 2134181 2134202 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC145285.6 chr16 28822431 28823969 - AD000090.1 chr19 35557956 35581954 + AF233439.1 chr8 6835535 6885276 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.