exRNAdisease

Entry Detail

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General Information

Database ID: exR0760747 RNA Name: MRFAP1 RNA Type: mRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 6640091 End Site(bp): 6642745 External Links: ENSG00000179010

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AASS chr7 122073549 122144255 - ABCC1 chr16 15949577 16143074 + ABCD4 chr14 74285269 74303055 - AC009133.6 chr16 29812261 29820092 + AC023055.1 chr12 55757275 55827546 - AC118553.2 chr1 99970011 100083321 + AC245033.1 chr15 82536788 82573194 - ACSL3 chr2 222860942 222944639 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADGRL2 chr1 81306160 81992436 + AFDN chr6 167826922 167972023 + AK8 chr9 132725578 132878777 - AKIRIN1 chr1 38991276 39006059 + ALDH18A1 chr10 95605941 95656711 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-330-3p chr19 45639009 45639031 - hsa-miR-708-5p chr11 79402077 79402099 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004540.1 chr7 26398593 26497595 + AC010542.4 chr16 66549280 66551189 + AC079781.5 chr7 97851688 97972985 - AC093827.4 chr4 86924630 86936202 - AC097478.1 chr4 89743792 89744305 + AC106864.1 chr4 112693047 112706810 - AC126365.1 chr17 20788071 20789584 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.