exRNAdisease

Entry Detail

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General Information

Database ID: exR0760863 RNA Name: MT-ATP6 RNA Type: mRNA Chromosome: chrMT Starnd: + Coordinate: Start Site(bp): 8527 End Site(bp): 9207 External Links: ENSG00000198899

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAK1 chr2 69457997 69674349 - AC004922.1 chr7 99325879 99394653 + AC012254.2 chr18 47108188 47176345 - AC091167.2 chr15 90249556 90272208 + AC138811.2 chr16 18788063 18801519 - ACTR1A chr10 102461881 102502712 - ACTR3 chr2 113890063 113962596 + ACTR8 chr3 53867066 53882152 - ADD1 chr4 2843857 2930076 + ADNP2 chr18 80109262 80147523 + ADRA2A chr10 111077029 111080907 + AFAP1 chr4 7758714 7939926 - AFTPH chr2 64524305 64593005 + AHCY chr20 34280268 34311802 - AHNAK chr11 62433542 62556235 - AHSA1 chr14 77457870 77469472 + AJUBA chr14 22971177 22982551 - AK3 chr9 4709556 4742043 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004687.1 chr17 58330884 58332508 - AC007952.4 chr17 19112000 19112636 - AC016876.2 chr17 7581964 7584086 - AC018521.1 chr17 47945424 47981736 + AC020978.7 chr16 68224713 68227734 + AD000090.1 chr19 35557956 35581954 + AL049795.2 chr1 32170733 32176568 + AL138759.1 chr10 94577439 94611238 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.