exRNAdisease

Entry Detail

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General Information

Database ID: exR0760866 RNA Name: MT-CO2 RNA Type: mRNA Chromosome: chrMT Starnd: + Coordinate: Start Site(bp): 7586 End Site(bp): 8269 External Links: ENSG00000198712

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC048338.1 chr12 122207779 122266423 - AEBP2 chr12 19404045 19720801 + AIF1L chr9 131096476 131123152 + ABCC10 chr6 43427366 43450427 + ACTB chr7 5527148 5563784 - ADAM22 chr7 87934143 88202889 + AKT1 chr14 104769349 104795751 - ADCY9 chr16 3953387 4116442 - ACTN4 chr19 38647649 38731589 + ACTG1 chr17 81509971 81523847 - AC011511.1 chr19 10305427 10316009 - ABCA3 chr16 2275881 2340746 - ABHD17A chr19 1876810 1885547 - AKAP8L chr19 15380050 15419141 - ALDH1A2 chr15 57953424 58497866 - AL358113.1 chr9 69035747 69255187 + AC008764.1 chr19 16479067 16628204 - ACBD6 chr1 180269653 180502954 - ACTN1 chr14 68874143 68979440 - AL136295.4 chr14 24180395 24190416 - AC007192.1 chr19 18153158 18178117 + ACOT9 chrX 23701055 23766475 - AC091167.2 chr15 90249556 90272208 + AHI1 chr6 135283532 135497765 - ABCD1 chrX 153724856 153744755 + AL133352.1 chr10 100505628 100529881 - AFG3L2 chr18 12328944 12377227 - ABCC1 chr16 15949577 16143074 + AC010132.3 chr7 42909273 42932174 - AIG1 chr6 143060496 143341058 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1825 chr20 32237830 32237847 + hsa-miR-3648 chr21 8987026 8987046 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006064.5 chr12 6510275 6510522 + AC007952.4 chr17 19112000 19112636 - AC016876.2 chr17 7581964 7584086 - AC020663.1 chr16 4730115 4752565 - AC027307.2 chr19 1457670 1458580 - AC040162.3 chr16 67882461 67886367 + AC051619.7 chr15 45200325 45200632 - AC067930.1 chr8 143579636 143580670 + AC083880.1 chr7 139359032 139359566 - AC097478.1 chr4 89743792 89744305 + AC124312.3 chr15 25087661 25088896 + AC125257.1 chr17 41848518 41851447 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.