exRNAdisease

Entry Detail

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General Information

Database ID: exR0760867 RNA Name: MT-CO3 RNA Type: mRNA Chromosome: chrMT Starnd: + Coordinate: Start Site(bp): 9207 End Site(bp): 9990 External Links: ENSG00000198938

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACVR1 chr2 157736444 157876330 - ABCF1 chr6 30571393 30597179 + AGO4 chr1 35808016 35857890 + AHNAK chr11 62433542 62556235 - ACVR2B chr3 38453890 38493142 + AL358113.1 chr9 69035747 69255187 + ALDH5A1 chr6 24494867 24537207 + ACTL6A chr3 179562886 179588407 + AATF chr17 36948954 37056871 + AIF1L chr9 131096476 131123152 + AC004832.3 chr22 30409255 30428990 + AFDN chr6 167826922 167972023 + AC008878.3 chr19 7382834 7470241 + ADNP chr20 50888916 50931437 - ABLIM1 chr10 114431113 114768061 - ABI2 chr2 203328239 203447728 + AHSA1 chr14 77457870 77469472 + ACLY chr17 41866917 41930542 - AKAP1 chr17 57085092 57121346 + AL121845.2 chr20 63738270 63740398 + AL049697.1 chr6 87408012 87511634 + AC013394.1 chr15 92883413 92949230 + AC138811.2 chr16 18788063 18801519 - AL589666.1 chr6 85557978 85615234 - AIFM2 chr10 70098223 70132934 - ADRM1 chr20 62302093 62308862 + ACTG1 chr17 81509971 81523847 - ACO2 chr22 41469117 41528989 + AC023055.1 chr12 55757275 55827546 - ACAP2 chr3 195274745 195443044 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1244 chr2 231713368 231713393 + hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-4426 chr1 192716333 192716349 + hsa-miR-5100 chr10 42997630 42997651 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007780.1 chr17 68413623 68524949 + AC016876.2 chr17 7581964 7584086 - AC020663.1 chr16 4730115 4752565 - AC092910.3 chr3 120094895 120136783 + AC244090.1 chrX 154424380 154428479 - ACVR2B-AS1 chr3 38451027 38454820 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.