exRNAdisease

Entry Detail

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General Information

Database ID: exR0760872 RNA Name: MT-ND4 RNA Type: mRNA Chromosome: chrMT Starnd: + Coordinate: Start Site(bp): 10760 End Site(bp): 12137 External Links: ENSG00000198886

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ALDH18A1 chr10 95605941 95656711 - ADNP chr20 50888916 50931437 - ADGRL1 chr19 14147743 14206187 - AC040162.1 chr16 67929614 67936017 - AKAP1 chr17 57085092 57121346 + ACADVL chr17 7217125 7225266 + AL365205.1 chr6 41780349 41790141 + AC073896.1 chr12 56285916 56316059 - AC008403.1 chr19 48465837 48472431 + ACTG1 chr17 81509971 81523847 - AC011448.1 chr19 19516227 19536076 + AHCY chr20 34280268 34311802 - ADIPOR2 chr12 1688574 1788674 + AC091167.2 chr15 90249556 90272208 + AKAP12 chr6 151239967 151358559 + ADH5 chr4 99070978 99088801 - AHCYL1 chr1 109984765 110023742 + ACTR2 chr2 65227753 65271253 + AC139530.2 chr17 81703371 81720539 + AKAP10 chr17 19904302 19978343 - ACTB chr7 5527148 5563784 - ACTR1A chr10 102461881 102502712 - AAMP chr2 218264123 218270257 - ADCY1 chr7 45574140 45723116 + ALDH1B1 chr9 38392702 38398661 + AL139300.1 chr14 103562962 103685924 + ACTL6A chr3 179562886 179588407 + ABRACL chr6 139028745 139043302 + AEN chr15 88621337 88632281 + ABHD13 chr13 108218392 108234243 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6728-3p chr1 8866502 8866522 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand A1BG-AS1 chr19 58347718 58355455 + AC002470.2 chr22 20979462 20998121 + AC006504.5 chr19 27793431 27984984 + AC007952.4 chr17 19112000 19112636 - AC008124.1 chr12 45718046 45727775 - AC016876.2 chr17 7581964 7584086 - AC099329.1 chr3 42785087 42852428 - AC108010.1 chr7 128574751 128626473 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.