exRNAdisease

Entry Detail

---



General Information

Database ID: exR0760916 RNA Name: MTRNR2L1 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 22523111 End Site(bp): 22524663 External Links: ENSG00000256618

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACIN1 chr14 23058564 23095614 - AK2 chr1 33007940 33080996 - ACACA chr17 37084992 37406836 - AC006978.2 chr7 30362400 30412502 + AC020909.1 chr19 50415799 50428409 + AC004922.1 chr7 99325879 99394653 + ACTG1 chr17 81509971 81523847 - AC015813.2 chr17 57989038 58007246 - AC009133.6 chr16 29812261 29820092 + AC087289.3 chr17 75898645 75930129 - AL035078.4 chr11 31812391 32104665 + AK4 chr1 65147549 65232145 + AL360181.3 chr10 133380017 133420271 + ACLY chr17 41866917 41930542 - ACTG2 chr2 73892314 73919865 + AC116366.3 chr5 132410832 132646079 + AC139530.2 chr17 81703371 81720539 + ABI1 chr10 26746593 26861087 - ACSL4 chrX 109624244 109733403 - AKT1 chr14 104769349 104795751 - AC008750.8 chr19 51350373 51368099 - ACBD6 chr1 180269653 180502954 - AC073508.2 chr17 40627356 40665141 - AC120057.2 chr17 7240427 7244635 - AGMAT chr1 15571699 15585051 - AC134669.1 chr17 31305213 31318831 - ADAM17 chr2 9488486 9556732 - ABL1 chr9 130713016 130887675 + ACTB chr7 5527148 5563784 - AC068946.2 chr2 219209772 219222738 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-632 chr17 32350169 32350187 + hsa-miR-4315 chr17 45475408 45475425 - hsa-miR-4485-3p chr11 10508277 10508296 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004687.1 chr17 58330884 58332508 - AC007780.1 chr17 68413623 68524949 + AC007952.4 chr17 19112000 19112636 - AC009831.1 chr18 31942575 31944156 + AC016831.1 chr7 130876809 130913310 - AC016876.2 chr17 7581964 7584086 - AC021078.1 chr5 149494314 149504670 - AC060780.1 chr17 43148368 43171037 - AC067930.1 chr8 143579636 143580670 + AC079781.5 chr7 97851688 97972985 - AC092620.2 chr2 138599663 138602426 - AC098850.4 chr17 16788057 16816540 + AC104461.1 chr1 200333193 200478669 + AC113189.4 chr17 7439506 7445966 + AC126365.1 chr17 20788071 20789584 + AC129492.1 chr17 8079482 8081565 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + ADIRF-AS1 chr10 86965345 86971311 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.