Entry Detail


General Information

Database ID:exR0760960
RNA Name:MYH10
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):8474205End Site(bp):8630761
External Links:ENSG00000133026



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE106804
Description:Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:13
Number of Control:6
Number of Samples:19





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010132.3
chr7
42909273
42932174
-
AC011530.1
chr19
45779437
45785973
-
AC124312.1
chr15
24955034
25000276
+
ACTG1
chr17
81509971
81523847
-
ADA2
chr22
17178790
17258235
-
ADAR
chr1
154582057
154628013
-
AFDN
chr6
167826922
167972023
+
AGBL4
chr1
48532854
50023954
-
AGO1
chr1
35869808
35930532
+
AGO2
chr8
140520156
140635633
-
AKIRIN2
chr6
87674860
87702233
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-141-3p
chr12
6964155
6964176
+
hsa-miR-194-5p
chr11
64891404
64891425
-
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC139149.1
chr17
81514047
81527776
+
AC245014.3
chr1
145281116
145281462
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:29330365
Title:Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:Nat Commun. 2018 Jan 12;9(1):175.
Description:Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.