exRNAdisease

Entry Detail

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General Information

Database ID: exR0761213 RNA Name: NFATC2IP RNA Type: mRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 28950807 End Site(bp): 28967097 External Links: ENSG00000176953

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + ABCB10 chr1 229516582 229558707 - AC010422.3 chr19 12643831 12648397 - AC015813.2 chr17 57989038 58007246 - ACTB chr7 5527148 5563784 - ACTN4 chr19 38647649 38731589 + ADAM10 chr15 58588809 58749791 - ADCY1 chr7 45574140 45723116 + AGAP1 chr2 235494043 236131800 + AGFG1 chr2 227472152 227561214 + AGO1 chr1 35869808 35930532 + AGRN chr1 1020120 1056118 + AK4 chr1 65147549 65232145 + AL136295.5 chr14 24147548 24166452 + ALDH1A2 chr15 57953424 58497866 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009093.10 chr16 29139379 29331304 + AC025279.1 chr16 29291220 29372110 + AC026362.1 chr12 122975320 122982907 + AC132217.1 chr11 2129121 2129964 - AL136985.3 chr1 58715609 58771295 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.