Entry Detail


General Information

Database ID:exR0761216
RNA Name:NFE2L1
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):48048329End Site(bp):48061545
External Links:ENSG00000082641



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE106804
Description:Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:13
Number of Control:6
Number of Samples:19





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
ABT1
chr6
26596953
26600739
+
AC124312.1
chr15
24955034
25000276
+
ACTG1
chr17
81509971
81523847
-
ADCY3
chr2
24819169
24919839
-
AFDN
chr6
167826922
167972023
+
AHCY
chr20
34280268
34311802
-
AIMP2
chr7
6009255
6023834
+
AL139300.1
chr14
103562962
103685924
+
AL713999.1
chr1
155169409
155187272
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-199a-5p
chr1
172144592
172144614
-
hsa-miR-148a-3p
chr7
25949922
25949943
-
hsa-miR-199b-5p
chr9
128244783
128244805
-
hsa-miR-371a-3p
chr19
53787716
53787738
+
hsa-miR-483-3p
chr11
2134142
2134162
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC109460.3
chr16
28974804
28990775
+
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:29330365
Title:Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:Nat Commun. 2018 Jan 12;9(1):175.
Description:Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.