exRNAdisease

Entry Detail

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General Information

Database ID: exR0761289 RNA Name: NME2 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 51165435 End Site(bp): 51171747 External Links: ENSG00000243678

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAR2 chr20 36236459 36270918 + AASDHPPT chr11 106075501 106098699 + ABHD6 chr3 58237532 58295693 + AC004832.3 chr22 30409255 30428990 + AC005258.1 chr19 2269525 2341172 + AC006030.1 chr2 74211604 74363377 - AC010422.3 chr19 12643831 12648397 - AC104472.3 chr3 155763043 155854442 - AC120057.2 chr17 7240427 7244635 - AC131160.1 chr3 183815568 183884889 - AC139530.2 chr17 81703371 81720539 + ACACA chr17 37084992 37406836 - ACBD6 chr1 180269653 180502954 - ACIN1 chr14 23058564 23095614 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACVR2B chr3 38453890 38493142 + ADAR chr1 154582057 154628013 - ADAT1 chr16 75596981 75623300 - ADGRG6 chr6 142301854 142446266 + AKAP1 chr17 57085092 57121346 + AKAP8L chr19 15380050 15419141 - AKAP9 chr7 91940867 92110673 + AKIRIN1 chr1 38991276 39006059 + AKR1A1 chr1 45550543 45570049 + AL133352.1 chr10 100505628 100529881 - AL513165.2 chr9 37512547 37592469 - AL590764.2 chrX 71103987 71111575 - ALDH2 chr12 111766887 111817532 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-206 chr6 52144401 52144422 + hsa-miR-302c-3p chr4 112648366 112648388 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004224.2 chr16 3458071 3515564 + AC020915.3 chr19 58257270 58278808 - AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.