exRNAdisease

Entry Detail

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General Information

Database ID: exR0761327 RNA Name: NOP53 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 47745546 End Site(bp): 47757058 External Links: ENSG00000105373

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC1 chr16 15949577 16143074 + ABHD3 chr18 21650901 21704780 - ABL1 chr9 130713016 130887675 + AC010422.3 chr19 12643831 12648397 - AC011455.2 chr19 38915404 38949855 - AC118553.2 chr1 99970011 100083321 + AC124312.1 chr15 24955034 25000276 + ACACA chr17 37084992 37406836 - ACADSB chr10 123008979 123058290 + ACIN1 chr14 23058564 23095614 - ACOT8 chr20 45841721 45857405 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + ACVR2B chr3 38453890 38493142 + ADAM11 chr17 44758988 44781846 + ADNP chr20 50888916 50931437 - AGPAT1 chr6 32168212 32178096 - AHCYL1 chr1 109984765 110023742 + AHR chr7 16916359 17346152 + AIP chr11 67483026 67491103 + AL121594.1 chr14 35122549 35317474 + AL136531.2 chr20 1317571 1393096 - AL355987.1 chr9 136738167 136748453 - AL928654.3 chr14 105487199 105492267 + ALDH6A1 chr14 74056847 74084492 - ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC021078.1 chr5 149494314 149504670 - AD000090.1 chr19 35557956 35581954 + AL132780.1 chr14 22929607 22956374 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.