exRNAdisease

Entry Detail

---



General Information

Database ID: exR0761358 RNA Name: NPM1 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 171387116 End Site(bp): 171411137 External Links: ENSG00000181163

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC073508.2 chr17 40627356 40665141 - AL121594.1 chr14 35122549 35317474 + AC092143.1 chr16 89919165 89936092 + AC007192.1 chr19 18153158 18178117 + ACTB chr7 5527148 5563784 - ADH5 chr4 99070978 99088801 - AC138969.1 chr16 16317444 16350590 + ABCC1 chr16 15949577 16143074 + AC008982.1 chr19 38817471 38840178 - AC004922.1 chr7 99325879 99394653 + AL365205.1 chr6 41780349 41790141 + ADD1 chr4 2843857 2930076 + AC126283.2 chr4 109713916 109801999 - AC005258.1 chr19 2269525 2341172 + AL031708.1 chr16 1632259 1686715 + AL139011.2 chr1 160216800 160285130 - ADAM23 chr2 206443532 206621127 + ABT1 chr6 26596953 26600739 + ALDH2 chr12 111766887 111817532 + AGPAT5 chr8 6708642 6761503 + ADGRG6 chr6 142301854 142446266 + AC120057.2 chr17 7240427 7244635 - ACTG1 chr17 81509971 81523847 - AHCYL1 chr1 109984765 110023742 + AACS chr12 125065434 125143333 + ADGRD1 chr12 130953907 131141469 + ALDH18A1 chr10 95605941 95656711 - ALDH3A2 chr17 19648136 19685760 + ACTR1A chr10 102461881 102502712 - AC010463.1 chr19 17267418 17282966 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007218.1 chr16 9666885 9676843 - AC007952.4 chr17 19112000 19112636 - AC011498.1 chr19 4457962 4471493 - AC022140.1 chr5 25404733 25445925 - AD000090.1 chr19 35557956 35581954 + AL021707.1 chr22 38739003 38749041 + AL137003.1 chr6 16764346 16766883 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.