exRNAdisease

Entry Detail

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General Information

Database ID: exR0761455 RNA Name: NUDT21 RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 56429133 End Site(bp): 56452199 External Links: ENSG00000167005

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD4 chr14 22598237 22613215 + AC005020.2 chr7 99558695 99607810 + AC005670.2 chr17 46923133 47049932 + AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC027796.3 chr17 3585149 3636249 - AC093525.2 chr16 2496032 2520218 + AC245033.1 chr15 82536788 82573194 - ACAA2 chr18 49782164 49813953 - ACSL4 chrX 109624244 109733403 - ACTB chr7 5527148 5563784 - ACVR2B chr3 38453890 38493142 + ADAM10 chr15 58588809 58749791 - ADH5 chr4 99070978 99088801 - AGFG1 chr2 227472152 227561214 + AHCY chr20 34280268 34311802 - AHCYL1 chr1 109984765 110023742 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-17-5p chr13 91350618 91350640 + hsa-miR-93-5p chr7 100093815 100093837 - hsa-miR-193b-3p chr16 14304017 14304038 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010442.1 chr5 466124 473098 - AC092490.1 chr12 8788253 8795789 + AC245033.4 chr15 82533175 82540008 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.