exRNAdisease

Entry Detail

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General Information

Database ID: exR0761501 RNA Name: OAZ1 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 2269509 End Site(bp): 2273490 External Links: ENSG00000104904

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAGAB chr15 67200667 67255195 - ABCB8 chr7 151028422 151047782 + ABL2 chr1 179099330 179229684 - AC005258.1 chr19 2269525 2341172 + AC006030.1 chr2 74211604 74363377 - AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC011455.2 chr19 38915404 38949855 - AC073508.2 chr17 40627356 40665141 - AC104109.3 chr5 134167170 134226071 - AC124312.1 chr15 24955034 25000276 + ACAT2 chr6 159762045 159779112 + ACLY chr17 41866917 41930542 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTL6A chr3 179562886 179588407 + ACTN1 chr14 68874143 68979440 - ACTR8 chr3 53867066 53882152 - ADAR chr1 154582057 154628013 - AEN chr15 88621337 88632281 + AHCTF1 chr1 246839098 246931967 - AHSA1 chr14 77457870 77469472 + AIFM1 chrX 130129362 130165887 - AKAP1 chr17 57085092 57121346 + AL133352.1 chr10 100505628 100529881 - AL139260.3 chr1 38864501 38881617 - ALCAM chr3 105366909 105576900 + ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC009908.1 chr8 124996985 124998198 - AC067930.1 chr8 143579636 143580670 + AC079145.1 chr2 19990209 20004795 + AC087392.5 chr17 795306 795794 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.