exRNAdisease

Entry Detail

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General Information

Database ID: exR0761658 RNA Name: P4HB RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 81843161 End Site(bp): 81860624 External Links: ENSG00000185624

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB7 chrX 75051048 75156732 - ABCF2 chr7 151207837 151227166 - ABLIM1 chr10 114431113 114768061 - ABR chr17 1003518 1229738 - AC010132.3 chr7 42909273 42932174 - AC015813.2 chr17 57989038 58007246 - AC087289.3 chr17 75898645 75930129 - ACAD11 chr3 132558138 132660082 - ACLY chr17 41866917 41930542 - ACOT9 chrX 23701055 23766475 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + ADD2 chr2 70607618 70768225 - ADORA2A chr22 24417879 24442357 + ADPRHL2 chr1 36088892 36093932 + ADSL chr22 40346500 40390463 + AGRN chr1 1020120 1056118 + AHCY chr20 34280268 34311802 - AK2 chr1 33007940 33080996 - AKR1B1 chr7 134442356 134459284 - AKT1 chr14 104769349 104795751 - AL022238.4 chr22 40346529 40410054 + AL121758.1 chr20 646626 675800 - AL590764.2 chrX 71103987 71111575 - ALDH1B1 chr9 38392702 38398661 + ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC055860.1 chr11 18000542 18022931 - AC060780.1 chr17 43148368 43171037 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.