exRNAdisease

Entry Detail

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General Information

Database ID: exR0761722 RNA Name: PARP1 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 226360691 End Site(bp): 226408093 External Links: ENSG00000143799

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD14B chr3 51968510 51983409 - ABL1 chr9 130713016 130887675 + ABRACL chr6 139028745 139043302 + ABTB1 chr3 127672935 127680926 + AC010323.1 chr19 8308283 8321379 - AC010422.3 chr19 12643831 12648397 - AC011462.1 chr19 41350853 41425001 + AC027796.3 chr17 3585149 3636249 - AC048338.1 chr12 122207779 122266423 - AC245033.1 chr15 82536788 82573194 - ACOT13 chr6 24667035 24705065 + ACSF2 chr17 50426158 50474845 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADGRA3 chr4 22345071 22516066 - ADH5 chr4 99070978 99088801 - ADRM1 chr20 62302093 62308862 + AGL chr1 99850361 99924023 + AL117348.2 chr1 225886696 225924278 - AL162417.1 chr9 133098121 133163914 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-496 chr14 101060628 101060649 + hsa-miR-556-3p chr1 162342600 162342621 + hsa-miR-4700-3p chr12 120723233 120723258 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009831.1 chr18 31942575 31944156 + AC106864.1 chr4 112693047 112706810 - AC132217.1 chr11 2129121 2129964 - AC245014.3 chr1 145281116 145281462 + AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.