exRNAdisease

Entry Detail

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General Information

Database ID: exR0761910 RNA Name: PGAM1 RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 97426191 End Site(bp): 97433444 External Links: ENSG00000171314

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AASDHPPT chr11 106075501 106098699 + ABCB6 chr2 219209772 219218994 - ABHD17C chr15 80679684 80755621 + ABI2 chr2 203328239 203447728 + ABL2 chr1 179099330 179229684 - AC007846.2 chr17 5772926 6080792 + AC073082.1 chr2 48632291 48755724 - AC091959.3 chr5 146203550 146339251 + AC110275.1 chr8 43018424 43077334 + AC139530.2 chr17 81703371 81720539 + AC245033.1 chr15 82536788 82573194 - ACACA chr17 37084992 37406836 - ACAT2 chr6 159762045 159779112 + ACBD7 chr10 15075475 15088776 - ACTB chr7 5527148 5563784 - ACTR1A chr10 102461881 102502712 - ACTR1B chr2 97655939 97664044 - ADA chr20 44619522 44652233 - ADAR chr1 154582057 154628013 - ADD2 chr2 70607618 70768225 - AFAP1 chr4 7758714 7939926 - AGBL5 chr2 27042364 27070622 + AKT2 chr19 40230317 40285536 - AL024498.2 chr6 10747794 10930423 + AL157392.5 chr10 13610047 13655929 + ALDH18A1 chr10 95605941 95656711 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-423-5p chr17 30117095 30117117 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009022.1 chr16 69976297 70065948 - AC026461.1 chr16 56682470 56687807 + AC245033.4 chr15 82533175 82540008 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.