exRNAdisease

Entry Detail

---



General Information

Database ID: exR0761920 RNA Name: PGK1 RNA Type: mRNA Chromosome: chrX Starnd: + Coordinate: Start Site(bp): 77910739 End Site(bp): 78129295 External Links: ENSG00000102144

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AIFM2 chr10 70098223 70132934 - AC012254.2 chr18 47108188 47176345 - AKIRIN2 chr6 87674860 87702233 - AHSA1 chr14 77457870 77469472 + AC011005.1 chr7 129126518 129130793 + ADPGK chr15 72751369 72785846 - AKIRIN1 chr1 38991276 39006059 + ABCC5 chr3 183919934 184017939 - ABCB7 chrX 75051048 75156732 - AFF4 chr5 132875395 132963634 - ADCY5 chr3 123282296 123449758 - AL121753.1 chr20 35267885 35280043 - AC010422.5 chr19 12664828 12669397 - AGGF1 chr5 77029251 77065234 + ACTG1 chr17 81509971 81523847 - ADGRB2 chr1 31727117 31764893 - ABCE1 chr4 145098288 145129524 + ACTR3 chr2 113890063 113962596 + AC023055.1 chr12 55757275 55827546 - AL355987.1 chr9 136738167 136748453 - ADH5 chr4 99070978 99088801 - ACAT1 chr11 108116695 108147603 + AC008581.2 chr5 77030902 77152155 + AFTPH chr2 64524305 64593005 + AAMP chr2 218264123 218270257 - ALDOA chr16 30064164 30070457 + ACTB chr7 5527148 5563784 - AL133352.1 chr10 100505628 100529881 - ALDH3A2 chr17 19648136 19685760 + AGFG1 chr2 227472152 227561214 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-29b-3p chr7 130877467 130877489 - hsa-miR-30c-5p chr6 71377003 71377025 - hsa-miR-136-5p chr14 100884716 100884738 + hsa-miR-299-3p chr14 101023832 101023853 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC000068.1 chr22 19447893 19450105 + AC007952.4 chr17 19112000 19112636 - AC020663.1 chr16 4730115 4752565 - AC023509.1 chr12 53441741 53467528 + AC048341.2 chr12 62603909 62604399 + AC074183.1 chr7 84939349 84940245 - AC079781.5 chr7 97851688 97972985 - AC091132.5 chr17 45549781 45558738 - AC106864.1 chr4 112693047 112706810 - AC113189.4 chr17 7439506 7445966 + AC132217.1 chr11 2129121 2129964 - AC133644.3 chr2 87455476 87767359 + AL022311.1 chr22 37876148 37895563 + AL137026.2 chr10 44259602 44261813 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.