exRNAdisease

Entry Detail

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General Information

Database ID: exR0762171 RNA Name: PODXL RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 131500262 End Site(bp): 131558217 External Links: ENSG00000128567

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004922.1 chr7 99325879 99394653 + AC005943.1 chr19 1578339 1605445 - AC010422.3 chr19 12643831 12648397 - AC073508.2 chr17 40627356 40665141 - AC091167.2 chr15 90249556 90272208 + AC118553.2 chr1 99970011 100083321 + AC135050.2 chr16 31083439 31094956 - ACAA2 chr18 49782164 49813953 - ACAD8 chr11 134253495 134265855 + ACP1 chr2 264140 278283 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR1A chr10 102461881 102502712 - ADCY3 chr2 24819169 24919839 - ADD3 chr10 109996368 110135565 + AFDN chr6 167826922 167972023 + AHCY chr20 34280268 34311802 - AIF1L chr9 131096476 131123152 + AKT1 chr14 104769349 104795751 - AKT1S1 chr19 49869033 49878459 - AL133352.1 chr10 100505628 100529881 - AL162417.1 chr9 133098121 133163914 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-4709-5p chr14 74480175 74480196 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.