exRNAdisease

Entry Detail

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General Information

Database ID: exR0762369 RNA Name: PRDX5 RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 64318121 End Site(bp): 64321811 External Links: ENSG00000126432

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005258.1 chr19 2269525 2341172 + AC006030.1 chr2 74211604 74363377 - AC007192.1 chr19 18153158 18178117 + AC010422.3 chr19 12643831 12648397 - AC120057.2 chr17 7240427 7244635 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADAM19 chr5 157395534 157575775 - ADGRL2 chr1 81306160 81992436 + ADRM1 chr20 62302093 62308862 + AGPAT5 chr8 6708642 6761503 + AK2 chr1 33007940 33080996 - AKIRIN1 chr1 38991276 39006059 + AKR1A1 chr1 45550543 45570049 + AL121594.1 chr14 35122549 35317474 + AL139011.2 chr1 160216800 160285130 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-4709-5p chr14 74480175 74480196 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC022167.2 chr16 8848105 8860456 + AC023509.1 chr12 53441741 53467528 + AC093462.1 chr18 54268346 54270028 - AC139149.1 chr17 81514047 81527776 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.