exRNAdisease

Entry Detail

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General Information

Database ID: exR0762659 RNA Name: RAB1A RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 65070696 End Site(bp): 65130331 External Links: ENSG00000138069

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010132.3 chr7 42909273 42932174 - AC010422.3 chr19 12643831 12648397 - AC011455.2 chr19 38915404 38949855 - AC091167.2 chr15 90249556 90272208 + AC245033.1 chr15 82536788 82573194 - ACTB chr7 5527148 5563784 - AK6 chr5 69350984 69370013 - AKAP8 chr19 15353385 15379798 - AL136531.2 chr20 1317571 1393096 - ALAS1 chr3 52198086 52214327 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-302b-3p chr4 112648489 112648511 - hsa-miR-302c-5p chr4 112648402 112648423 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL021707.1 chr22 38739003 38749041 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.