exRNAdisease

Entry Detail

---



General Information

Database ID: exR0762708 RNA Name: RACK1 RNA Type: mRNA Chromosome: chr5 Starnd: - Coordinate: Start Site(bp): 181236897 End Site(bp): 181248096 External Links: ENSG00000204628

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF2 chr7 151207837 151227166 - AL136454.1 chr1 192716132 192716653 + AGPAT5 chr8 6708642 6761503 + ACTB chr7 5527148 5563784 - ACTR8 chr3 53867066 53882152 - AC010522.1 chr19 57819719 57858941 + ACTR2 chr2 65227753 65271253 + AC005258.1 chr19 2269525 2341172 + ADPRH chr3 119579268 119589945 + AL021997.3 chr6 28267121 28281580 + ACTN1 chr14 68874143 68979440 - ALDH2 chr12 111766887 111817532 + ABHD18 chr4 127965306 128039927 + AL121753.1 chr20 35267885 35280043 - AFDN chr6 167826922 167972023 + AL049629.2 chr11 33698261 33722467 - AC008764.4 chr19 16577642 16660115 - ADAM33 chr20 3667965 3682246 - AJUBA chr14 22971177 22982551 - AHCY chr20 34280268 34311802 - AC138811.2 chr16 18788063 18801519 - ACOT9 chrX 23701055 23766475 - AHNAK chr11 62433542 62556235 - AC087289.3 chr17 75898645 75930129 - ALDH18A1 chr10 95605941 95656711 - ALDH6A1 chr14 74056847 74084492 - AL033529.1 chr1 32465057 32600792 + AC004922.1 chr7 99325879 99394653 + AC068946.2 chr2 219209772 219222738 - ACAA2 chr18 49782164 49813953 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3610 chr8 116874740 116874759 - hsa-miR-4426 chr1 192716333 192716349 + hsa-miR-4709-3p chr14 74480135 74480157 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC008267.5 chr7 66493607 66495758 + AC016876.2 chr17 7581964 7584086 - AC051619.7 chr15 45200325 45200632 - AC078846.1 chr7 129604548 129611630 - AC079781.5 chr7 97851688 97972985 - AC092171.3 chr7 5426277 5428927 - AC097478.1 chr4 89743792 89744305 + AC132217.1 chr11 2129121 2129964 - AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL023653.1 chrX 129794994 129796963 + AL096870.2 chr14 24209646 24215987 - AL121992.1 chr1 15586136 15603626 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.