exRNAdisease

Entry Detail

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General Information

Database ID: exR0762739 RNA Name: RAN RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 130872037 End Site(bp): 130877678 External Links: ENSG00000132341

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABT1 chr6 26596953 26600739 + AC004997.1 chr22 30285238 30299482 - AC006030.1 chr2 74211604 74363377 - AC010132.3 chr7 42909273 42932174 - AC092073.1 chr19 34396315 34409364 + AC124312.1 chr15 24955034 25000276 + AC135050.2 chr16 31083439 31094956 - ACAA2 chr18 49782164 49813953 - ACADVL chr17 7217125 7225266 + ACIN1 chr14 23058564 23095614 - ACO1 chr9 32384603 32454769 + ACO2 chr22 41469117 41528989 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR5 chr20 38748460 38772520 + ADAT3 chr19 1905399 1913447 + ADCY3 chr2 24819169 24919839 - ADGRG1 chr16 57610652 57665580 + ADH5 chr4 99070978 99088801 - ADSL chr22 40346500 40390463 + AEN chr15 88621337 88632281 + AFDN chr6 167826922 167972023 + AGO3 chr1 35930718 36072500 + AGPAT3 chr21 43865223 43987592 + AIF1L chr9 131096476 131123152 + AKAP1 chr17 57085092 57121346 + AKIRIN1 chr1 38991276 39006059 + AL021546.1 chr12 120438198 120460006 + AL022238.4 chr22 40346529 40410054 + AL136295.4 chr14 24180395 24190416 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-302b-3p chr4 112648489 112648511 - hsa-miR-302a-5p chr4 112648224 112648246 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012236.1 chr15 31221999 31230838 - AC079781.5 chr7 97851688 97972985 - AC106864.1 chr4 112693047 112706810 - AC113189.4 chr17 7439506 7445966 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.