exRNAdisease

Entry Detail

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General Information

Database ID: exR0762854 RNA Name: RCC2 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 17406760 End Site(bp): 17439677 External Links: ENSG00000179051

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002996.1 chr12 111753890 111791418 + AC007192.1 chr19 18153158 18178117 + AC010422.3 chr19 12643831 12648397 - AC091167.2 chr15 90249556 90272208 + AC097637.1 chr3 52221081 52231190 - ACTA1 chr1 229431245 229434098 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADCY5 chr3 123282296 123449758 - ADD3 chr10 109996368 110135565 + AL133352.1 chr10 100505628 100529881 - AL136454.1 chr1 192716132 192716653 + ALDH18A1 chr10 95605941 95656711 - ALDH1B1 chr9 38392702 38398661 + ALDH2 chr12 111766887 111817532 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-7-5p chr19 4770700 4770723 + hsa-miR-204-5p chr9 70810031 70810052 - hsa-miR-211-5p chr15 31065095 31065116 - hsa-miR-149-5p chr2 240456015 240456037 + hsa-miR-485-5p chr14 101055427 101055448 + hsa-miR-519c-5p chr19 53686484 53686505 + hsa-miR-620 chr12 116148575 116148594 - hsa-miR-519b-5p chr19 53695225 53695246 + hsa-miR-1270 chr19 20399320 20399342 - hsa-miR-4468 chr7 138123803 138123820 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.