exRNAdisease

Entry Detail

General Information

Database ID:

exR0762997

RNA Name:

RIT1

RNA Type:

mRNA

Chromosome:

chr1

Starnd:

-

Coordinate:

Start Site(bp):

155897808

End Site(bp):

155911404

External Links:

ENSG00000143622

Disease Information

Disease Name:	Glioblastoma Multiforme
Disease Category:	Cancers
MeSH ID:	D005909
Type:	Neoplasms/Neoplasms, Glandular and Epithelial
Alias:	Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID:	GSE106804
Description:	Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:	Cancer vs Control
Case Disease Type:	Glioblastoma Multiforme
Case Disease SubType:	NA
Case Sample:	Glioblastoma Multiforme
Control Sample:	Healthy
Number of Case:	13
Number of Control:	6
Number of Samples:	19

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ACTG1	chr17	81509971	81523847	-
ADAMTS19	chr5	129460281	129738683	+
ALDH18A1	chr10	95605941	95656711	-

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-17-5p	chr13	91350618	91350640	+
hsa-miR-20a-5p	chr13	91351072	91351094	+
hsa-miR-302a-3p	chr4	112648186	112648208	-
hsa-miR-302c-3p	chr4	112648366	112648388	-
hsa-miR-302d-3p	chr4	112648006	112648028	-
hsa-miR-373-3p	chr19	53788748	53788770	+
hsa-miR-20b-5p	chrX	134169850	134169872	-
hsa-miR-512-3p	chr19	53666729	53666750	+

circRNA targets:

NA

lncRNA targets:

NA

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	29330365
Title:	Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:	Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:	Nat Commun. 2018 Jan 12;9(1):175.
Description:	Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.